401k Record

Employers › Karyopharm Therapeutics

Karyopharm Therapeutics 401(k)

Recordkeeping fees per participant · Karyopharm Therapeutics Inc. 401(k) Plan · plan year 2024

$129.91

Higher than 85% of the 5,847 plans $50 to 250M that report it.

Source

= $62,878 / 484
Schedule H, line 2i(3); OTH_RECORDKEEPING_FEES_AMT pos 160; filing 20250730133715NAL0001967235001, received 2025-07-30
participants_with_balance: Form 5500, line 6g(2); PARTCP_ACCOUNT_BAL_CNT pos 78; filing 20250730133715NAL0001967235001, received 2025-07-30

10th: $10.22median $69.9190th: $151.08

Percentiles compare this plan with the Schedule H plans $50 to 250M in assets of the same plan year, excluding final filings; shown only where at least 50 comparable plans report the figure. Plan year 2024-01-01 to 2024-12-31, filing received 2025-07-30.

Cost and contributions

Administrative expenses excluding investment management, per participant

$129.91

10th: $16.21median $93.2090th: $246.84

Higher than 68% of the 8,758 plans $50 to 250M that report it.

Source

= $62,878 / 484
derived, admin_expenses (2i(12)) minus invst_mgmt_fees (2i(5)), floored at 0; filing 20250730133715NAL0001967235001, received 2025-07-30
participants_with_balance: Form 5500, line 6g(2); PARTCP_ACCOUNT_BAL_CNT pos 78; filing 20250730133715NAL0001967235001, received 2025-07-30

Administrative expenses per participant

$129.91

10th: $29.39median $132.8490th: $350.58

Higher than 49% of the 9,042 plans $50 to 250M that report it.

Source

= $62,878 / 484
Schedule H, line 2i(12) total administrative expenses; TOT_ADMIN_EXPENSES_AMT pos 109; filing 20250730133715NAL0001967235001, received 2025-07-30
participants_with_balance: Form 5500, line 6g(2); PARTCP_ACCOUNT_BAL_CNT pos 78; filing 20250730133715NAL0001967235001, received 2025-07-30

Administrative expenses as a share of assets

0.113%

10th: 0.022%median 0.136%90th: 0.326%

Higher than 42% of the 9,049 plans $50 to 250M that report it.

Source

= $62,878 / $55,627,157
Schedule H, line 2i(12) total administrative expenses; TOT_ADMIN_EXPENSES_AMT pos 109; filing 20250730133715NAL0001967235001, received 2025-07-30
assets_eoy: Schedule H, Part I line 1f col (b); TOT_ASSETS_EOY_AMT pos 61; filing 20250730133715NAL0001967235001, received 2025-07-30

Employer contributions per participant

$5,192

10th: $965median $2,73890th: $8,164

Higher than 78% of the 9,105 plans $50 to 250M that report it.

Source

= $2,512,829 / 484
Schedule H, Part II line 2a(1)(A); EMPLR_CONTRIB_INCOME_AMT pos 68; filing 20250730133715NAL0001967235001, received 2025-07-30
participants_with_balance: Form 5500, line 6g(2); PARTCP_ACCOUNT_BAL_CNT pos 78; filing 20250730133715NAL0001967235001, received 2025-07-30

Employer share of total contributions

26.1%

10th: 15.6%median 29.5%90th: 50.6%

Higher than 38% of the 9,112 plans $50 to 250M that report it.

Source

= $2,512,829 / $9,624,780
Schedule H, Part II line 2a(1)(A); EMPLR_CONTRIB_INCOME_AMT pos 68; filing 20250730133715NAL0001967235001, received 2025-07-30
total_contrib: Schedule H, line 2a(3); TOT_CONTRIB_AMT pos 72; filing 20250730133715NAL0001967235001, received 2025-07-30

Plan terms, as stated in Karyopharm Therapeutics Inc.'s SEC filings

Employer match

“The 401(k) Plan allows each participant to contribute a portion of their base wages up to an amount not to exceed an annual statutory maximum and the Company provides a match up to 4% of components of employee compensation.”

Form 10-K filed 2026-02-13, for the year ended 2025-12-31 · benefits note, 10-K benefits note · source document

Terms quoted from the filing for the year ended 2025-12-31. Figures cover plan year 2024. The plan document governs.

Plan features

2E profit-sharing · 2F ERISA 404(c) plan · 2G fully participant-directed · 2J 401(k) feature · 2K 401(m) arrangement · 2T default investment (QDIA) · 3D IRS pre-approved plan · Form 5500, line 8a; TYPE_PENSION_BNFT_CODE pos 81; filing 20250730133715NAL0001967235001, received 2025-07-30

Full record, Karyopharm Therapeutics Inc. 401(k) Plan

FieldValueSource
Plan sponsorKARYOPHARM THERAPEUTICS INC.Form 5500, Part II line 2a; SPONSOR_DFE_NAME pos 19; filing 20250730133715NAL0001967235001, received 2025-07-30
Plan nameKARYOPHARM THERAPEUTICS INC. 401(K) PLANForm 5500, line 1a; PLAN_NAME pos 16; filing 20250730133715NAL0001967235001, received 2025-07-30
Sponsor EIN / plan number26-3931704 / 001Form 5500, line 2b; SPONS_DFE_EIN pos 44; filing 20250730133715NAL0001967235001, received 2025-07-30
Plan typesingle-employerForm 5500, Part I line A; TYPE_PLAN_ENTITY_CD pos 4; filing 20250730133715NAL0001967235001, received 2025-07-30
Sponsor locationNEWTON, MAForm 5500, line 2a; SPONS_DFE_MAIL_US_STATE pos 25; filing 20250730133715NAL0001967235001, received 2025-07-30
Industry (business code)325410, ManufacturingForm 5500, line 2d; BUSINESS_CODE pos 46; filing 20250730133715NAL0001967235001, received 2025-07-30
Plan year2024-01-01 to 2024-12-31Form 5500, Part I plan year; FORM_PLAN_YEAR_BEGIN_DATE pos 2; filing 20250730133715NAL0001967235001, received 2025-07-30
Filing received2025-07-30Form 5500, EFAST2 receipt date; DATE_RECEIVED pos 102; filing 20250730133715NAL0001967235001, received 2025-07-30
Final filingnoForm 5500, Part I line B; FINAL_FILING_IND pos 8; filing 20250730133715NAL0001967235001, received 2025-07-30
Amended filingyesForm 5500, Part I line B; AMENDED_IND pos 7; filing 20250730133715NAL0001967235001, received 2025-07-30
Participants, beginning of year546Form 5500, line 5; TOT_PARTCP_BOY_CNT pos 71; filing 20250730133715NAL0001967235001, received 2025-07-30
Active participants284Form 5500, line 6a(2); TOT_ACTIVE_PARTCP_CNT pos 72; filing 20250730133715NAL0001967235001, received 2025-07-30
Participants, end of year503Form 5500, line 6f; TOT_ACT_RTD_SEP_BENEF_CNT pos 77; filing 20250730133715NAL0001967235001, received 2025-07-30
Participants with an account balance484Form 5500, line 6g(2); PARTCP_ACCOUNT_BAL_CNT pos 78; filing 20250730133715NAL0001967235001, received 2025-07-30
Total assets, beginning of year$46,052,253Schedule H, Part I line 1f col (a); TOT_ASSETS_BOY_AMT pos 30; filing 20250730133715NAL0001967235001, received 2025-07-30
Total assets, end of year$55,627,157Schedule H, Part I line 1f col (b); TOT_ASSETS_EOY_AMT pos 61; filing 20250730133715NAL0001967235001, received 2025-07-30
Net assets, end of year$55,627,157Schedule H, line 1l col (b); NET_ASSETS_EOY_AMT pos 67; filing 20250730133715NAL0001967235001, received 2025-07-30
Total income$17,063,253Schedule H, Part II line 2d; TOT_INCOME_AMT pos 97; filing 20250730133715NAL0001967235001, received 2025-07-30
Net income$9,574,904Schedule H, line 2k; NET_INCOME_AMT pos 111; filing 20250730133715NAL0001967235001, received 2025-07-30
Employer contributions$2,512,829Schedule H, Part II line 2a(1)(A); EMPLR_CONTRIB_INCOME_AMT pos 68; filing 20250730133715NAL0001967235001, received 2025-07-30
Participant contributions$5,505,491Schedule H, line 2a(1)(B); PARTICIPANT_CONTRIB_AMT pos 69; filing 20250730133715NAL0001967235001, received 2025-07-30
Other contributions (incl. rollovers)$1,606,460Schedule H, line 2a(1)(C); OTH_CONTRIB_RCVD_AMT pos 70; filing 20250730133715NAL0001967235001, received 2025-07-30
Total contributions$9,624,780Schedule H, line 2a(3); TOT_CONTRIB_AMT pos 72; filing 20250730133715NAL0001967235001, received 2025-07-30
Benefit payments$7,413,977Schedule H, line 2e(4); TOT_DISTRIB_BNFT_AMT pos 101; filing 20250730133715NAL0001967235001, received 2025-07-30
Total expenses (incl. benefit payments)$7,488,349Schedule H, line 2j; TOT_EXPENSES_AMT pos 110; filing 20250730133715NAL0001967235001, received 2025-07-30
Total administrative expenses$62,878Schedule H, line 2i(12) total administrative expenses; TOT_ADMIN_EXPENSES_AMT pos 109; filing 20250730133715NAL0001967235001, received 2025-07-30
Contract administrator fees$0Schedule H, line 2i(2); CONTRACT_ADMIN_FEES_AMT pos 106; filing 20250730133715NAL0001967235001, received 2025-07-30
Recordkeeping fees$62,878Schedule H, line 2i(3); OTH_RECORDKEEPING_FEES_AMT pos 160; filing 20250730133715NAL0001967235001, received 2025-07-30
IQPA audit fees$0Schedule H, line 2i(4); IQPA_AUDIT_FEES_AMT pos 161; filing 20250730133715NAL0001967235001, received 2025-07-30
Investment advisory and management fees$0Schedule H, line 2i(5); INVST_MGMT_FEES_AMT pos 107; filing 20250730133715NAL0001967235001, received 2025-07-30
Administrative expenses excluding investment management$62,878derived, admin_expenses (2i(12)) minus invst_mgmt_fees (2i(5)), floored at 0; filing 20250730133715NAL0001967235001, received 2025-07-30
Held in master trusts$0Schedule H, line 1c(11) col (b); INT_MASTER_TR_EOY_AMT pos 53; filing 20250730133715NAL0001967235001, received 2025-07-30
Held in common/collective trusts$0Schedule H, line 1c(9) col (b); INT_COMMON_TR_EOY_AMT pos 51; filing 20250730133715NAL0001967235001, received 2025-07-30
Held in mutual funds$54,722,482Schedule H, line 1c(13) col (b); INT_REG_INVST_CO_EOY_AMT pos 55; filing 20250730133715NAL0001967235001, received 2025-07-30
Independent auditorCBIZ CPAS P.C.Schedule H, Part III line 3a; ACCOUNTANT_FIRM_NAME pos 116; filing 20250730133715NAL0001967235001, received 2025-07-30

Position = column in the DOL layout for form year 2024. Filing 20250730133715NAL0001967235001, received 2025-07-30.

Service providers paid directly by the plan

ProviderRelationshipService codesDirect compensationIndirect
FIDELITY INVESTMENTS INSTITUTIONALrecordkeeperRECORDKEEPER 37 Participant loan processing; 64 Recordkeeping fees; 65 Account maintenance fees $62,878yes

Schedule C Part I line 2: name (a), service codes (b), relationship (c), direct compensation paid by the plan (d), indirect compensation received (e). Filing 20250730133715NAL0001967235001, received 2025-07-30.

What changed since the 2023 plan year

Figure20232024Change
Total assets$46,052,253$55,627,15720.8%
Participants with a balance523484-7.5%
Administrative expenses$50,144$62,87825.4%
Recordkeeping fees per participant$95.88$129.9135.5%
Employer contributions$3,213,687$2,512,829-21.8%

Prior filing 20240910114713NAL0009880848001, received 2024-09-10; the plan years are contiguous.

Alerts, claims and corrections

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Sponsor name as filed: KARYOPHARM THERAPEUTICS INC.; SEC registrant: Karyopharm Therapeutics Inc. (CIK 1503802, matched by EIN; display name from the Form 10-K cover).